Allopurinol

Of over the counter and gout related prescription medicines, allopurinol is one of the more popular gout related prescription medicines available but being chemically based one might experience side effects when take daily.

Gout Care on the other hand being a natural product has none of these side effect:

 

 

“ I have been taking the Gout Care product for almost a year now and  have found it more effective than the Allopurinol that had been  prescribed by my doctor.  Far fewer attacks and generally less inflammation” .*

Michael Downes, August 2015  SA.

*Results differ from one person to the next and can not be guaranteed.

Allopurinol has also been shown to have many potential side effects including, skin rashes, allergic reactions including vomiting, fever, chills, nausea, abdominal pain and diarrhea. It is also known when you start taking allopurinol that it may actually increase the chance of more gout attacks? Isn’t this the reason you’re taking it ? To stop gout attacks, not create more?! Apparently you also need to discuss the chances of stroke and heart attack with your doctor while taking allopurinol.

 

Prescription gout treatment is not typically advised for asymptomatic hyperuricemia (high uric acid levels with no gout attack symptoms). These traditional gout drugs should only be prescribed by informed doctors, in the presence of gout attacks or kidney stones. The undesired side effects associated with these gout drugs, and the damage that they may do to the organs, does not warrant their use based solely on elevated uric acid levels in the blood. GC® GoutCare, on the other hand, can be used by both gout sufferers and people with high blood levels of uric acid. GC® is safe and only has beneficial side effects from its use, for anyone with or without uric acid problems. In fact, GC® has a positive effect on type two Diabetics by aiding to lower their insulin needs. It is even possible to control borderline cases in hopes of remaining off insulin altogether.

 

ALLOPURINOL (Zyloprim)(a prescription drug) inhibits uric acid synthesis and has been linked to skin eruptions, inflammation of the blood vessels, and liver toxicity. Periodic liver enzymes, renal function tests and complete blood counts should be performed in all patients on allopurinol. Alterations in liver enzymes, including transient elevations of serum alkaline phosphatase, AST and ALT, have occurred in some patients. Reversible hepatomegaly, hepatocellular damage (including necrosis), granulomatous changes, hepatitis and jaundice have also occurred.

COLCHICINE (a prescription drug) is used to alleviate attacks. This drug can cause serious side effects and toxicity and even death in high doses.Side Effects: 80% of people who take colchicine in doses that are high enough to be effective develop stomach problems, such as cramping, nausea, diarrhea, or vomiting. Serious side effects of colchicine include bone marrow problems, muscle inflammation, severe anemia, and extremely low white blood counts that can increase the risk of infection developing. Colchicine is usually avoided or the dose adjusted in people who have reduced kidney function.

Allopurinol (also called Zyloprim and other generic names) is a drug used primarily to treat hyperuricemia (excess uric acid in blood plasma) and its complications, including chronic gout. It is a xanthine oxidase inhibitor which is administered orally. Subsequently the uric acid lowering capacity of allopurinol was noted, and the drug went on to be developed for its more famous use: to treat hyperuricemia (excess uric acid in blood plasma) and its complications. Allopurinol does not alleviate acute attacks of gout, and there is currently controversy over the issue of whether it can actually make acute gout attacks worse initially, but is useful in chronic gout to prevent future attacks.

Side-effects:

Because allopurinol is not a uricosuric, it can be used in patients with poor kidney function. However, allopurinol has two important disadvantages.

 

First, its dosing is complex. Second, some patients are hypersensitive to the drug, therefore its use requires careful monitoring. Allopurinol has rare but potentially adverse effects involving the skin. The most serious adverse effect is a hypersensitivity syndrome consisting of fever, skin rash, eosinophilia, hepatitis, worsened renal function, and, in some cases, allopurinol hypersensitivity syndrome.

Allopurinol is one of the drugs commonly known to cause Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TENS), two life-threatening dermatological conditions. More common is a less-serious rash that leads to discontinuing this drug. Studies have found HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions that include Steven Johnson Syndrome and toxic epidermal necrosis caused by allopurinol.

 

More rarely, allopurinol can also result in the depression of bone marrow elements, leading to cytopenias, as well as aplastic anemia. Moreover, allopurinol can also cause peripheral neuritis in some patients, although this is a rare side effect. Another side effect of allopurinol is interstitial nephritis.[23]

It is suspected to cause congenital malformations when used during pregnancy, and should be avoided whenever possible by women trying to conceive.

Dextrothyroxine (trade name Choloxin) saw research as an cholesterol-lowering drug but was pulled due to cardiac side-effects. It also increases hepatic lipase which in turn improves utilization of triglycerides, improving apo lipoprotein E cholesterol particles.

 

Antibiotics

When used by a person who suffers with high uric acid it can be a problem. Antibiotics kills friendly bacteria in the digestive system and since the bowels account for about 30% of the uric acid elimination in our bodies, a uric acid build in the blood may happen when on antibiotics.

The antibiotics seem to inhibit the elimination of uric acid from the bowel system due to the bacteria not being present. It also may hamper the herbal blend from being absorbed fully into the system, due to the elimination of the lactobacillus-bifidus / acidophilus by the antibiotics. Therefore a person using our herbal blend and has a need to take antibiotics must be very careful with their diet during and after its use. The person also should consume extra sour dairy and acidophilus / bifidus pills during and after to re-establish a proper working bowel system before they indulge in foods high in purines again.